Transcriptional Control of Brown Fat Development
نویسندگان
چکیده
منابع مشابه
Transcription regulators and hormones involved in the development of brown fat and white fat browning. Transcriptional and hormonal control of brown/beige fat development.
The high prevalence of obesity and related metabolic complications has inspired research on adipose tissues. Three kinds of adipose tissues are identified in mammals: brown adipose tissue (BAT), beige or brite adipose tissue and white adipose tissue (WAT). Beige adipocytes share some characteristics with brown adipocytes such as the expression of UCP1. Beige adipocytes can be activated by envir...
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Brown and beige adipose tissue is specialized for heat production and can be activated to reduce obesity and metabolic dysfunction in animals. Recent studies also have indicated that human brown fat activity levels correlate with leanness. This has revitalized interest in brown fat biology and has driven the discovery of many new regulators of brown fat development and function. This review sum...
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15 صفحه اولTranscriptional control of brown adipocyte development and physiological function--of mice and men.
The last several years have seen an explosion of information relating to the transcriptional control of brown fat cell development. At the same time, new data have emerged that clearly demonstrate that adult humans do indeed have substantial amounts of functioning brown adipose tissue (BAT). Together, these advances are stimulating a reassessment of the role of brown adipose tissue in human phy...
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ژورنال
عنوان ژورنال: Cell Metabolism
سال: 2010
ISSN: 1550-4131
DOI: 10.1016/j.cmet.2010.03.005